Various projects have made use of OBS data since the study’s inception in 2013. These projects have been incredibly successful and have resulted in publications, which are listed below, organized from most to least recent.


  • Lye JM, Knight JA, Arneja J, Seeto RA, Wong J, Khani NA, Brooks JD, Levitan RD, Matthews SG, Lye SJ, Hung RJ.┬áMaternal acetaminophen use and cognitive development at 4 years: the Ontario Birth Study.┬áPediatric Research. 2022 July. doi: 10.1038/s41390-022-02182-w.


  • Steckle V*, Shynlova O*,Lye S, Bocking A. Exercise, inflammation, and spontaneous preterm labor. Applied Physiology, Nutrition, and Metabolism. 2021 Apr; 46(4):337-345. doi: 10.1139/apnm-2019-0911. Epub 2020 Sep 25


  • Sasaki A, Kim B, Murphy KE, Matthews SG. Impact of ex vivo Sample Handling on DNA Methylation Profiles in Human Cord Blood and Neonatal Dried Blood Spots. Front Genet. 2020 Mar 24;11:224. doi: 10.3389/fgene.2020.00224. PMID: 32265984; PMCID: PMC7106936.
  • Arneja J, Hung RJ, Seeto RA, Knight JA, Hewko SL, Bocking A, Lye SJ, Brooks JD. Association between maternal acetaminophen use and adverse birth outcomes in a pregnancy and birth cohort. Pediatr Res. 2020 Jun;87(7):1263-1269. doi: 10.1038/s41390-019-0726-8. Epub 2019 Dec 18. PMID: 31852009.
  • Levitan RD, Sqapi M, Atkinson L, Murphy K, Levitt A, Bocking A, Post M, Knight JA, Matthews SG. Seasonality of plasma tryptophan and kynurenine in pregnant mothers with a history of seasonal affective disorder: Vulnerability or adaptation? World J Biol Psychiatry. 2020 Sep;21(7):529-538. doi: 10.1080/15622975.2020.1769189. Epub 2020 May 28. Erratum in: World J Biol Psychiatry. 2020 Jun 26;:1. PMID: 32462949.
  • Steckle V, Shynlova O, Lye S, Bocking A. Low-intensity physical activity may protect pregnant women against spontaneous preterm labor: A prospective case-control study. Appl Physiol Nutr Metab. 2020 Sep 25. doi: 10.1139/apnm-2019-0911. Epub ahead of print. PMID: 32976725.
  • Levitan RD, Zhang CXW, Knight JA, Hung R, Lye J, Murphy K, Atkinson L, Bocking A, Lye S, Matthews SG. Using Precision Medicine with a Neurodevelopmental Perspective to Study Inflammation and Depression. Curr Psychiatry Rep. 2020 Dec 8;22(12):87. doi: 10.1007/s11920-020-01206-8. PMID: 33289044.
  • Michalski CA, Hung RJ, Seeto RA, Dennis CL, Brooks JD, Henderson J, Levitan R, Lye SJ, Matthews SG, Knight JA. Association between maternal cannabis use and birth outcomes: an observational study. BMC Pregnancy Childbirth. 2020 Dec 11;20(1):771. doi: 10.1186/s12884-020-03371-3. PMID: 33308186; PMCID: PMC7731469.


  • Poole N, Schmidt RA, Bocking A, Bergeron J, Fortier I. The Potential for Fetal Alcohol Spectrum Disorder Prevention of a Harmonized Approach to Data Collection about Alcohol Use in Pregnancy Cohort Studies. Int J Environ Res Public Health. 2019 Jun 6;16(11):2019. doi: 10.3390/ijerph16112019. PMID: 31174290; PMCID: PMC6603946.
  • Paquette AG, Shynlova O, Wu X, Kibschull M, Wang K, Price ND, Lye SJ. MicroRNA-transcriptome networks in whole blood and monocytes of women undergoing preterm labour. J Cell Mol Med. 2019 Oct;23(10):6835-6845. doi: 10.1111/jcmm.14567. Epub 2019 Jul 24. PMID: 31342622; PMCID: PMC6787570.
  • Furmli H, Seeto RA, Hewko SL, Dalfen A, Jones CA, Murphy KE, Bocking A. Maternal Mental Health in Assisted and Natural Conception: A Prospective Cohort Study. J Obstet Gynaecol Can. 2019 Nov;41(11):1608-1615. doi: 10.1016/j.jogc.2019.03.002. Epub 2019 Jul 25. PMID: 31351834.


  • Paquette AG, Shynlova O, Kibschull M, Price ND, Lye SJ; Global Alliance to Prevent Prematurity and Stillbirth Systems Biology of Preterm Birth Team. Comparative analysis of gene expression in maternal peripheral blood and monocytes during spontaneous preterm labor. Am J Obstet Gynecol. 2018 Mar;218(3):345.e1-345.e30. doi: 10.1016/j.ajog.2017.12.234. Epub 2018 Jan 2. PMID: 29305255.
  • Anderson LN, Knight JA, Hung RJ, Hewko SL, Seeto RA, Martin MJ, Fleming A, Maguire JL, Matthews SG, Murphy KE, Okun N, Jenkins JM, Lye SJ, Bocking A; Ontario Birth Study Collaboration. The Ontario Birth Study: A prospective pregnancy cohort study integrating perinatal research into clinical care. Paediatr Perinat Epidemiol. 2018 May;32(3):290-301. doi: 10.1111/ppe.12473. Epub 2018 May 11. PMID: 29750375.
  • Fallen S, Baxter D, Wu X, Kim TK, Shynlova O, Lee MY, Scherler K, Lye S, Hood L, Wang K. Extracellular vesicle RNAs reflect placenta dysfunction and are a biomarker source for preterm labour. J Cell Mol Med. 2018 May;22(5):2760-2773. doi: 10.1111/jcmm.13570. Epub 2018 Mar 8. PMID: 29516617; PMCID: PMC5908130.
  • Freitas AC, Bocking A, Hill JE, Money DM; VOGUE Research Group. Increased richness and diversity of the vaginal microbiota and spontaneous preterm birth. Microbiome. 2018 Jun 28;6(1):117. doi: 10.1186/s40168-018-0502-8. PMID: 29954448; PMCID: PMC6022438.


  • Christiaens I, Ang QW, Gordon LN, Fang X, Williams SM, Pennell CE, Olson DM. Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth. BMC Med Genet. 2015 Aug 11;16:59. doi: 10.1186/s12881-015-0205-y. PMID: 26260058; PMCID: PMC4593185.