The overall aim of the Ontario Birth Study is to develop a platform for research on pregnancy complications, maternal and infant health, and to assemble a cohort for future studies on the developmental origins of health and disease.

We conduct studies of both pregnancy complications (e.g., preterm birth, preterm premature rupture of membranes, hypertensive diseases in pregnancy and fetal growth restriction) as well as the developmental origins of health and disease.

photo of pregnant woman

The OBS also serves as a platform for future multidisciplinary studies with novel research goals.

Examples of these goals are:

  1. to identify informative biomarkers and define molecular mechanisms responsible for the major pregnancy complications such as growth restriction, preeclampsia and preterm birth
  2. to determine how adversity during pregnancy and early life impact the establishment of developmental trajectories to later life health, learning and social functioning, and
  3. through the promotion of interventions that seek to optimize individual developmental trajectories, to enhance developmental potential and prevent or mitigate the impact of early adversity.